4-CHLORO-3-METHYLPYRIDINE (4-CHLORO-3-PICOLINE)
4-Chloro-3-methylpyridine
CAS: 1681-36-3
Molecular Formula: C6H6ClN
4-CHLORO-3-METHYLPYRIDINE (4-CHLORO-3-PICOLINE) - Names and Identifiers
| Name | 4-Chloro-3-methylpyridine |
| Synonyms | 4-CHLORO-3-PICOLINE 4-Chloro-3-Picoline 4-chloro-3-picoline HCI 4-Chloro-3-methylpyridine 3-Methyl-4-Chloropyridine 4-Chloro-5-methylpyridine 4-CHLORO-3-METHYLPYRIDINE 3-methyl-4-chloropyridine HCl 4-Chloro-3-methylpyridine HCl Salt 3-Methyl-4-ChloropyridineHydrochloride 4-CHLORO-3-METHYLPYRIDINE (4-CHLORO-3-PICOLINE) |
| CAS | 1681-36-3 |
| EINECS | 671-799-7 |
| InChI | InChI=1/C6H6ClN.ClH/c1-5-4-8-3-2-6(5)7;/h2-4H,1H3;1H |
4-CHLORO-3-METHYLPYRIDINE (4-CHLORO-3-PICOLINE) - Physico-chemical Properties
| Molecular Formula | C6H6ClN |
| Molar Mass | 127.57 |
| Density | 1,17 g/cm |
| Melting Point | 165-169°C(lit.) |
| Boling Point | 192-193 C |
| Flash Point | 75 ºC |
| Vapor Presure | 0.101mmHg at 25°C |
| pKa | 3.44±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1,533 |
| Physical and Chemical Properties | WGK Germany:3 |
4-CHLORO-3-METHYLPYRIDINE (4-CHLORO-3-PICOLINE) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
4-CHLORO-3-METHYLPYRIDINE (4-CHLORO-3-PICOLINE) - Introduction
4-choro-3-methylpyriridine is an organic compound with the chemical formula C6H6ClN. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 4-choro-3-methylpyriridine is a colorless to light yellow liquid or crystalline solid.
-water-soluble: insoluble in water, soluble in most organic solvents.
-Melting point: About -9 ℃.
-Boiling point: About 230 ℃.
-Density: Approximately 1.16 g/mL.
Use:
-Industrial use: 4-choro-3-methylpyriridine is commonly used as a catalyst and solvent in organic synthesis.
-Medical use: It is also a commonly used pharmaceutical intermediate, which can be used to synthesize drugs.
-Agricultural use: 4-chloro-3-methylpyriridine can also be used in agricultural fields as a pesticide and fungicide.
Method:
A common preparation method of 4-chloro-3-methylpyriridine is generated by reacting 3-methylpyridine with hydrogen chloride.
Safety Information:
-4-choro-3-methylpyridine is irritating to the skin and eyes, rinse thoroughly with water after contact.
-It may also cause some degree of acute and chronic toxicity to health, so appropriate protective measures should be taken when using it.
-Avoid inhaling its vapor during use and ensure that it is operated in a well-ventilated place.
-Please follow the relevant safety operation guidelines and store it away from fire and high temperature.
Nature:
-Appearance: 4-choro-3-methylpyriridine is a colorless to light yellow liquid or crystalline solid.
-water-soluble: insoluble in water, soluble in most organic solvents.
-Melting point: About -9 ℃.
-Boiling point: About 230 ℃.
-Density: Approximately 1.16 g/mL.
Use:
-Industrial use: 4-choro-3-methylpyriridine is commonly used as a catalyst and solvent in organic synthesis.
-Medical use: It is also a commonly used pharmaceutical intermediate, which can be used to synthesize drugs.
-Agricultural use: 4-chloro-3-methylpyriridine can also be used in agricultural fields as a pesticide and fungicide.
Method:
A common preparation method of 4-chloro-3-methylpyriridine is generated by reacting 3-methylpyridine with hydrogen chloride.
Safety Information:
-4-choro-3-methylpyridine is irritating to the skin and eyes, rinse thoroughly with water after contact.
-It may also cause some degree of acute and chronic toxicity to health, so appropriate protective measures should be taken when using it.
-Avoid inhaling its vapor during use and ensure that it is operated in a well-ventilated place.
-Please follow the relevant safety operation guidelines and store it away from fire and high temperature.
Last Update：2024-04-09 20:49:11
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